Graph Power: Uncovering the Value of Relationships in Life Sciences

Graph technology is allowing pharma to model data in a way that offers invaluable insights for marketing, R&D, and compliance teams alike.

Google, Facebook and LinkedIn are among those utilizing graph technology, which can model real-world relationships in a way that was not possible in the past.

Life sciences industry is leading the way in the adoption of this technology. It can share data seamlessly and uncover relationships hidden in broad ranges of data sets, making it invaluable to R&D and commercial teams alike.

This article examines the advantages of graph-based multi-model data storage technology over traditional databases and analytics, and considers what the future of data management in life sciences may hold.

Why graphs?

A graph is made up of nodes – real-life entities, like health care providers (HCPs), Integrated Delivery Networks (IDNs) and products – that can be connected to signify relationships. Relationship could be employee, prescriber, or caregiver. The number of nodes and relationships that can be managed is unlimited. This model can represent real-world relationships much more clearly than relational databases that have rigid schemas.

Leading consumer applications, like LinkedIn and Facebook, utilize graphs to easily identify and visualize complex relationships in a simple interface. This technology is an elegant, powerful way to solve complex data problems.

When HCPs, products, healthcare organizations (HCOs) and locations are connected in many-to-many relationships, it reveals valuable insights than traditional databases cannot. Graph technology can quickly identify an HCP’s channel choice, content preferences, influence in a disease area, prescribed product,s and clinical trial participation, for example. The graph helps model the roll-up of dynamic hierarchical information, such as revenue, value, or prescription by site of care, and also aids in finding key influencers, which makes clinical trials data management faster and more efficient than the legacy solutions.


The power of a multi-model data architecture with graph 

Companies need a flexible, reliable data foundation that can handle information from internal, external and third-party data sources, and has big data scalability. Commercial and medical teams want the power to uncover the relationships HCPs, key opinion leaders or key accounts have with various organizations, products and locations. Data models need to be updated quickly, without impacting performance. A columnar database cannot easily support relationships, which is a challenge for traditional RDBMS-based master data management solutions. Introducing a new relationship in a relational database when business needs change is complicated and resource-intensive.

However, while pure graph databases are suited to managing relationships, they don’t have the scalability to incorporate interactions and transactions at big data level. A multi-model approach (the idea that a single business application should be able to connect to different database types to create a business solution), with columnar-graph hybrid stores, is more suitable for applications with varying data storage needs. Moreover, it provides an agile approach, which offers the flexibility to model complex relationships without the burden of re-implementation when business needs change.

Responsive data management platforms offer such a hybrid, which enables schema-on-read, graph relationship definition and infinite horizontal scalability across all business entities with limitless attributes.

Graph analytics for relevant insights 

Responsive data management platforms also provide mechanisms to ensure data reliability, integrity and governance, as well as matching appropriate data entities across multiple systems and devices. Graph and big data analytics technologies make a powerful combination. Such technology can provide support for data science queries, graph analytics, window functions, percentile calculations, and advanced machine learning. It also offers advanced algorithms, such as page ranks, triangles, node connectivity and node degree, allowing users to learn more about the relationships between data entities. Teams can quickly determine top-selling drugs in target segments or group HCPs based on their specialty, locations and prescription profiles. They can analyze publications, clinical trial participation and speaking engagements to find key opinion leaders (KOLs).

Thanks to predictive analytics and machine learning, customer relationship management becomes agile and actionable in real time. Medical Science Liaison (MSL) teams can uncover new relationships quickly, and provide field teams with intelligent recommendations for effective customer engagement.

Applications in life sciences

The use of graphs in life sciences allows commercial, medical and brand teams to gauge the influence of physicians, and their relationships and affiliations with hospitals and other institutions. This allows them to identify HCPs who play a significant role in decision making.

Here are a few examples of how data-driven applications that leverage graph technology can provide better access and customer insights.

Affiliation management 

Understanding professional and organizational relationships is crucial. Graph technology provides data-driven affiliation management of all relationships within and across HCOs and HCPs. This supports commercial operations by providing the ability to correlate plans, actions and results. Commercial teams get graphical views of HCP-to-HCO affiliations and HCP-to-HCP relationships, as well as legal structures of HCO-to-HCO hierarchies, including IDNs, hospitals, clinics, departments, labs and nursing homes.

Key account management (KAM) 

Successful KAM strategy requires a convergence of information from all functional areas and applications and a keen understanding of the relationships across the account. Data-driven graph applications provide reliable data and recommend actions to develop and nurture relationships with targeted individuals. Account teams can measure and rank HCP influence against any criteria, and determine the value or credit risk of an account with hierarchy roll-ups.

Plan-payer management 

With the healthcare industry’s focus on outcomes-based medicine, payers need to curtail the costs of expensive therapies and apply stringent rules to formulary access. With graph technology, life sciences executives can easily see the relationship between formulary status and prescription data, which was traditionally stored in an inaccessible data warehouse. They can also find relationships between HCPs and payers, and target them specialty care drugs.

Key opinion leader (KOL) management 

The success or failure of a clinical trial or product launch significantly depends on recruiting the right investigator or KOL. Graph technology provides full demographic profiles and affiliation, and an audit history of prior engagement and outcomes.


Graph technology can support the allocation of training for the field force and account teams to comply with rules and regulations. This yields significant savings and improves productivity by proactively identifying reps who do not need training. It can also produce compliance reports that meet transparency reporting requirements.

Product brand management

Building a product master on a responsive data management platform with graph relationships provides universal identification and complies with the US IDMP (Identification of Medicinal Products) by linking and synchronizing product data across all sources. The graph becomes the single repository for all product master reference data, transaction and interaction data related to products, and even product intelligence from third-party data sources. It provides the definition of flexible product hierarchies by markets, brands, segments and geographies. This information can then be categorized, organized and analyzed from multiple perspectives, and presented to the end user in the context most suited to their roles and objectives.

The applications of graphs in life sciences are extensive and impactful. The technology provides unprecedented visibility into the complex relationships among HCPs, HCOs, plans, payers, products and locations.

Once scattered across systems, now graphs make this information available to commercial, brand and medical teams in easy-to-use data-driven applications. Teams can quickly discover relationships, identify target customers and navigate complex hierarchies to execute their plans of action efficiently.


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